منابع مشابه
Homing therapy
The BDNF-induced increase (left) in synapses (red) on a neuron (green) is lost if í µí»-catenin and cadherin are locked together (right). S tem cells become much more effi cient at muscle repair if they fi rst get a boost of cytokines and migratory adhesion molecules, report Galvez et al. (page 231). The improved repair stems from better homing abilities. Skeletal muscle can be repaired by a c...
متن کاملStrategies to Improve Homing of Stem Cells to achieve better Efficacy in Stem Cell Therapy
Stem/progenitor cell based therapeutic approach in our daily routine clinical practice, has been elusive dream in medical sciences and improvement of stem cell homing as one of major challenges in cell therapy programs, has been considered a promising milestone. It has been proved that stem/progenitor cells exhibit a homing response to injured tissues/organs, mediated by interactions of chemoki...
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Current clinical methods for cancer diagnosis and therapy have limitations, although survival periods are increasing as medical technologies develop. In most cancer cases, patient survival is closely related to cancer stage. Late-stage cancer after metastasis is very challenging to cure because current surgical removal of cancer is not precise enough and significantly affects bystander normal t...
متن کاملstrategies to improve homing of stem cells to achieve better efficacy in stem cell therapy
stem/progenitor cell based therapeutic approach in our daily routine clinical practice, has been elusive dream in medical sciences and improvement of stem cell homing as one of major challenges in cell therapy programs, has been considered a promising milestone. it has been proved that stem/progenitor cells exhibit a homing response to injured tissues/organs, mediated by interactions of chemoki...
متن کاملRecirculation and Homing of Lymphocyte Subsets: Dual Homing Specificity
The p7-integrin subunit can pair with two a-chains, a4 and aE, and is expressed mainly on lymphocytes. As an a4-heterodimer it binds to the mucosal addressin MAdCAM-1, thus acting as a mucosal homing receptor. As an aE-heterodimer it binds to E-cadherin and is mainly found on intestinal intraepithelial lymphocytes. Consequently, p7 is mostly expressed on lymphocytes of the mucosal immune system...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2006
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.1742iti1